Phospho tbk1 antibody

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August undefined, 2024

WebThis product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free production For … WebDec 9, 2013 · TBK1 is phosphorylated in its activation loop, leading to IRF3/7 activation and Type I interferon (IFN) production. IPS-1 and STING localize to the mitochondria and endoplasmic reticulum,...

(5483) Phospho-TBK1/NAK (Ser172) (D52C2) XP® Rabbit mAb

WebTBK1 [p Ser172] Antibody (EPR2867 (2)) Summary. Immunogen. A phospho specific peptide corresponding to residues surrounding serine 172 of human NAK/TBK1 was used … WebThe Phospho-TBK1/NAK (Ser172) (D52C2) XP ® Rabbit mAb Antibody has been validated for the following applications: Precipitation, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, and Western Blot. Phospho-TBK1/NAK (Ser172) (D52C2) XP® Rabbit mAb detects endogenous levels of TBK1 only when phosphorylated … great clips martinsburg west virginia

TBK1 Antibody (108A429) SCBT - Santa Cruz Biotechnology

WebMonoclonal antibody is prepared from animals immunized with a synthetic phosphopeptide corresponding to residues surrounding Ser172 of human TBK1. Validations. Biological … WebPhospho-TBK1 (Ser172) Antibody (MA5-35869) in WB Western Blot analysis of Phospho-TBK1 (Ser172) performed on various cell lines using a Phospho-TBK1 (Ser172) monoclonal antibody ( Product # MA5-35869) at a dilution of 1:1,000. An HRP Goat Anti-Rabbit IgG (H+L) secondary antibody was applied at a dilution of 1:10,000. Product Details great clips menomonie wi

Interferon-independent STING signaling promotes resistance to ... - Nature

Anti-phospho-TBK1 (Ser172) Antibody 07-2192

WebPhospho-TBK1/NAK (Ser172) (D52C2) XP ® Rabbit mAb (PE Conjugate) recognizes endogenous levels of TBK1 only when phosphorylated at Ser172. This antibody may … WebRecently, a new IKK family member, TBK1 [ (TANK-binding kinase), also known as NAK and T2K] has been identified. TANK (TRAF-associated NF-kB activator) interacts with TBK1 and activates NF-kB in a kinase dependent manner. Limitations This product is for research use only and is not approved for use in humans or in clinical diagnosis. great clips mckinney hardinWebOur TBK1 polyclonal, monoclonal, recombinant monoclonal and recombinant polyclonal antibodies are developed in Rabbit, Mouse and Goat. These antibodies have been verified by Knockdown, Knockout and Relative expression to confirm specificity to TBK1. Find the TBK1 antibody that fits your needs. great clips marketplace rochester mn

"WebTBK1 (TANK-binding kinase 1)/NAK (NF-κB activating kinase) is an IκB kinase (IKK)-activating kinase and can activate IKK through direct … " - Phospho tbk1 antibody

Phospho tbk1 antibody

TBK1 Antibody (108A429) SCBT - Santa Cruz Biotechnology

WebPhospho-TBK1 (Ser172) Antibody (PA5-13056) in DB Dot blot analysis of Phospho-TBK pSer172 polyclonal antibody ( Product # PA5-13056) on nitrocellulose membrane. 50 ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5 µg per mL. Product Details Product Specific Information WebWestern blot - Phospho-TBK1/NAK-S172 Rabbit pAb (AP0847) Western blot analysis of HeLa, using Phospho-TBK1/NAK-S172 antibody (AP0847) at 1:400 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit …

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WebWhile TBK1 is known to phosphorylate cargo receptors to promote ubiquitin binding, it is unknown whether TBK1 phosphorylates other proteins to promote mitophagy. Using global quantitative proteomics, we identified S72 in RAB7A, a RAB previously linked with mitophagy, as a dynamic target of TBK1 upon mitochondrial depolarization. WebThe Phospho-TBK1 (Ser172) assay measures TBK1 when phosphorylated at Ser172. Contrary to Western Blot, the assay is entirely plate-based and does not require gels, electrophoresis or transfer. The Phospho-TBK1 (Ser172) assay uses 2 labeled antibodies: one with a donor fluorophore, the other one with an acceptor.

WebApr 10, 2024 · Importance of Validating Antibodies and Small Compound Inhibitors Using Genetic Knockout Studies-T Cell Receptor-Induced CYLD Phosphorylation by IKKε/TBK1 as a Case Study Importance of Validating Antibodies and Small Compound Inhibitors Using Genetic Knockout Studies-T Cell Receptor-Induced CYLD Phosphorylation by IKKε/TBK1 … WebDec 1, 2024 · AMPK directly phosphorylates TBK1 at S511 to prime antiviral sensing • AMPK-TBK1 couples glucose deficiency sensing and innate immune surveillance • Targeting the AMPK-TBK1 axis compromises innate antiviral immunity Summary Nutrient sensing and damage sensing are two fundamental processes in living organisms.

WebAnti-phospho-TBK1 (Ser172) Antibody 07-2192 Sigma-Aldrich Anti-phospho-TBK1 (Ser172) Antibody Download Zoom This phospho-TBK1 antibody is validated for use in WB for the … WebPhospho-TBK1 (Ser172) Antibody (BS-3440R) in IHC (P) Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti-TBK1 (Ser172) …

WebAnti Phospho Tbk1 Ab, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more ... The following primary antibodies were obtained from Cell Signaling Technology: anti-phospho-CAMKII Ab ( p -CAMKII, 1:1000, …

WebJan 29, 2015 · Specification of TBK1-mediated IRF3 activation is essential for the tight regulation of IFN production, which would otherwise lead to autoimmune diseases. … great clips medford oregon online check inWebMonoclonal Antibody for studying TBK1 (Ser172) phosphate. Cited in 553 publications. Validated for WB, IP, IF, F. Available in 2 sizes. Highly specific and rigorously validated in-house, Phospho-TBK1/NAK (Ser172) (D52C2) XP® Rabbit Monoclonal Antibody (CST #5483) is ready to ship. great clips marshalls creekWebRecombinant Anti-NAK/TBK1 (phospho S172) antibody [EPR2867 (2)] - BSA and Azide free (ab186469) Datasheet Certificate of Compliance Submit a review Submit a question References (1) $905 Product size 100 µg $905 1 mg $8,985.00 Add to basket Order now and get it on Thursday March 02, 2024 Custom quote Bulk request Shipping info great clips medford online check inWebTBK1 Background NFkappaB-activating kinase (NAK) also known as TANK binding kinase-1 (TBK1) or tumor necrosis factor receptor−associated factor 2-associated kinase (T2K) is a serine/threonine protein that belongs to the IkB kinase (IKK) family (1). Similar to IKK alpha and beta (2), NAK induces IkB degradation and NF-kB activity. great clips medford njWebDec 10, 2015 · Immunofluorescence experiments using a phospho-TBK1 (pS-172) specific antibody on A549, H1650, Calu-6 and PC9 non-small cell lung cancer (NSCLC) cell lines as well as the immortalized human tracheobronchial epithelial cell line AALE established that phospho-TBK1 localized to centrosomal regions during prophase and prometaphase, … great clips medina ohWebThis product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility. - Improved sensitivity … great clips md locationsWebDec 10, 2015 · Phospho-TBK1 and total TBK1 were also present in additional fractions; correlating with the observation that phospho-TBK1 also is associated with spindle … great clips marion nc check in