WebMar 3, 2024 · According to the company, the primary endpoint of the REACH study will be changed in a reachable workspace (RWS), which is a measure of upper extremity range of motion critical to self-care and quality of life for FSHD patients WebThe primary endpoint of the study is the absolute change from baseline in Reachable Workspace (RWS). Secondary endpoints include muscle fat infiltration (MFI), Patient Global Impression of Change (PGIC), and Quality of Life in Neurological Disorders of the upper extremity (Neuro QoL UE).
Fulcrum Phase 3 FSHD Clinical Trial using AMRA Medical
WebMar 3, 2024 · About Reachable Workspace (RWS) RWS is a quantitative measure of upper extremity range of motion and function. Specifically, it evaluates total shoulder and … WebMay 31, 2024 · The Reachable Workspace will be used to measure change (s) from baseline in the participants upper extremity function. The Reachable Workspace is a clinical … fnf shaggy v3 download
Reachable workspace analysis is a potential measurement for …
WebJun 11, 2024 · Prediction of the reachable workspace. The experimental RWS was reconstructed from the motion capture data points for each load case as presented in Castro et al. (2024), while the musculoskeletal models simulated the RWS using the motion from the no-payload case corresponding to the active RWS. Even though the AMS … WebOct 1, 2024 · Assess efficacy of losmapimod to slow or stop disease progression with reachable workspace (RWS). RWS is a 3D assessment of function that measures upper extremity mobility. Fulcrum is developing losmapimod (LOS; a small molecule inhibitor of p38 α/β MAPK) to treat FSHD. WebThe research shows that functional composite measurements correlate with disease-relevant clinical outcome assessments such as reachable workspace (RWS) and timed-up-and-go (TUG). Also, through test-retest experiments, the data shows that whole-body composite scores are stable and reproducible between scans, suggesting the MRI … greenville health system children\u0027s hospital